Typically we try to cure diaper rashes with natural solutions however PJ had the worse diaper rash I have even seen last week. It was terrible and nothing on our changing table was fixing it. My mother came over with some Desitin for us to try, as my sister-in-law uses it on my nephew and she insisted we try. Although the smell is chemical, it did its job well and fast. We put it on my son at 8pm when he went to bed and by morning that pesky diaper rash was gone. Although this still will not be my first choice, it is something that we will definitely keep around for anything that the natural solutions cannot seem to fix.